Chai Discovery Secures $130M Series B, Valued at $1.3B

San Francisco, CA, December 15, 2025 (Yahoo Finance) -- OpenAI-backed biotech startup Chai Discovery raised $130 million in a Series B financing round, pushing its valuation to $1.3 billion. The round was led by General Catalyst and Oak HC/FT, with participation from Menlo Ventures, OpenAI, Thrive Capital, SV Angel, Emerson Collective, and others, bringing total funding to more than $225 million. Chai develops AI foundation models for drug discovery, and says its latest platform, Chai 2, significantly improves success rates in de novo antibody design by enabling the creation of drug-like molecules for previously hard-to-target diseases.

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