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Executive Spotlights

Sionna Therapeutics Announce $182M Series C Financing

Waltham, MA, March 8, 2024 (Cystic Fibrosis News Today) -- Sionna Therapeutics has secured $182 million in financing to propel the advancement of small molecules engineered to address cystic fibrosis (CF) by targeting a critical segment of the CFTR protein known as the first nucleotide-binding domain (NBD1). Founded in 2019 and incubated by investment firm RA Capital, the company aims to challenge Vertex Pharmaceuticals’ market-leading cystic fibrosis business. The company has 5 drugs in development, all of which work differently than Vertex’s medicines. Two are in clinical testing, and two more could join them by the end of 2024.


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